mHVEM-BT/160 mice have a similar phenotype to controls during Y. enterocolitica infection. Co-housed littermates were infected with 1.0 × 108Y. enterocolitica. KI, gene KI. (A) Survival curves in day 12 experiments. Data shown were analyzed by log-rank test. (B) Changes in body weight (percentage of baseline). The weights of mice that died during the experiment were carried forward. Data shown are mean ± SEM and analyzed by two-way ANOVA with Bonferroni’s multiple hypothesis correction. (A and B) Data represent pooled results from three independent experiments (n = 10–14 mice per group). (C) Representative H&E staining to detect necrotic areas and WS silver staining to detect bacteria in splenic and hepatic sections from the indicated mice at 7 d after infection. Scale bars, 100 µm. The histopathologic scores of H&E sections were evaluated as described in Materials and methods. Data shown are median for two-way ANOVA.
Figure S4.

mHVEM-BT/160 mice have a similar phenotype to controls during Y. enterocolitica infection. Co-housed littermates were infected with 1.0 × 108Y. enterocolitica. KI, gene KI. (A) Survival curves in day 12 experiments. Data shown were analyzed by log-rank test. (B) Changes in body weight (percentage of baseline). The weights of mice that died during the experiment were carried forward. Data shown are mean ± SEM and analyzed by two-way ANOVA with Bonferroni’s multiple hypothesis correction. (A and B) Data represent pooled results from three independent experiments (n = 10–14 mice per group). (C) Representative H&E staining to detect necrotic areas and WS silver staining to detect bacteria in splenic and hepatic sections from the indicated mice at 7 d after infection. Scale bars, 100 µm. The histopathologic scores of H&E sections were evaluated as described in Materials and methods. Data shown are median for two-way ANOVA.

This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal