Figure S2.

Delayed Vegfr2 deletion impairs vessel invasion and odontoblast maturation. (A) Protocol for 4OHT injection. (B and C) Gross appearance and quantification of body length of mice at P12 (control [Cont] n = 3, Vegfr2iΔECn = 3). (D–I) Immunohistochemistry of a mandible centered on the first molar and quantification (Cont n = 3, Vegfr2iΔECn = 3). (J) Tooth mechanical strength measured by a compression test (Cont n = 3, Vegfr2iΔECn = 3). Scale bars: 2 cm (B); 50 µm (D–G). Data are presented as means ± SD. Comparisons between two groups were evaluated using a two-sided Student’s t test.

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