Illustration of multiple-cleft FEM meshes and cleft conductance calculations. (A) Five example ID maps, illustrating variable but similar overall geometries. (B and C) Corresponding FEM meshes (B) and slices through the meshes above (C), illustrating variation in the lengths of plicate and interplicate regions, and GJs. (D) Distribution of cleft conductances (g_C) in each mesh, for M = 200 partitions. The black line represents the mean conductance for each mesh. Parameters: plicate membrane distance d_P = 30 nm, interplicate membrane distance d_IP = 15 nm.