Figure 1.
The cardiac ventricular myocyte thin filament landscape in a half sarcomere. The half sarcomere ultrastructure is divided into the Z-disc where the thin filament barbed ends are located, the I-band composed of thin filaments and the titin N2B and PEVK regions, the A-band that includes thin and thick filaments, and the M-band that contains thick filaments. The thick filaments are further divided into the D-zone, the C-zone that contains cMyBP-C, and the P-zone.