Figure S1.
Single ATP turnover measurements from multicellular ventricular preparations from wild-type and transgenic mice expressing myc-tag–labeled MyBP-C.(A) The lifetime of nucleotide turnover associated with fast phase of fluorescence decay. (B) The lifetime of nucleotide turnover associated with the slow (SRX) phase of fluorescence decay. (C) The amplitude of the slow phase of fluorescence decay, indicating the fraction of myosin molecules that adopted the SRX state. n = 4 wild-type mice (14 technical replicates) and n = 2 myc-tag–labeled MyBP-C mice (12 technical replicates). Error bars indicate ±SEM (P > 0.4).

Single ATP turnover measurements from multicellular ventricular preparations from wild-type and transgenic mice expressing myc-tag–labeled MyBP-C. (A) The lifetime of nucleotide turnover associated with fast phase of fluorescence decay. (B) The lifetime of nucleotide turnover associated with the slow (SRX) phase of fluorescence decay. (C) The amplitude of the slow phase of fluorescence decay, indicating the fraction of myosin molecules that adopted the SRX state. n = 4 wild-type mice (14 technical replicates) and n = 2 myc-tag–labeled MyBP-C mice (12 technical replicates). Error bars indicate ±SEM (P > 0.4).

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