Sarcomere dynamics and interplay between adjacent sarcomeres at various levels of LV contractility. (A) CI between adjacent sarcomeres at various levels of ΔLVP (i.e., between position 0 and 1 in Fig. 3 F, top). CI, −0.03 ± 0.35, −0.06 ± 0.28, 0.10 ± 0.27, −0.22 ± 0.32, −0.25 ± 0.13, and −0.43 ± 0.13 at 135.7, 96.4, 60.5, 40.6, 7.2, and 4.7 mm Hg, respectively. Horizontal bars, average; vertical bars, SD. *, P < 0.05; **, P < 0.01; and ***, P < 0.001 compared with 96.4 mm Hg. (B) Individual ΔSL at various levels of ΔLVP. ΔSL (maximal SL minus minimal SL): 0.43 ± 0.19, 0.56 ± 0.33, 0.55 ± 0.41, 0.39 ± 0.29, 1.11 ± 0.56, and 0.69 ± 0.25 µm at 135.7, 96.4, 60.5, 40.6, 7.2, and 4.7 mm Hg, respectively (compare Fig. S16). Horizontal bars, average; vertical bars, SD. *, P < 0.05; **, P < 0.01; and ***, P < 0.001 compared with 96.4 mm Hg. In A and B, data from two myofibrils were pooled for 96.4, 60.5, 40.6, and 7.2 mm Hg (Figs. 3, S6, and S18), and three myofibrils were pooled for 135.7 and 4.7 mm Hg (Figs. S15 and S18).