Figure 3. Fit of 16 CARs with the CHA 16... | Rockefeller University Press

Figure 3.

Fit of 16 CARs with the CHA16model. 7 ligand concentrations and 5 data points at each ligand concentration were chosen, summing up for the 16 CARs to 560 data points. The noise level was set to 0.25. The conditions were our standard conditions. The values for Zi and Ex as well as Ki are provided by Fig. 4, A and C, respectively. The fdx values (imprecisions) were fd1 = 7.022 (0.0354), fd2 = 7.42 × 10−3 (0.0289), fd3 = 1.11 × 10−4 (0.0357), and fd4 = 7.30 × 10−3 (0.0262). The brackets in the legends indicate closely similar data points and curves. The big gray double arrow illustrates that the CAR combination is varied.

Fit of 16 CARs with the CHA ₁₆ model. 7 ligand concentrations and 5 data points at each ligand concentration were chosen, summing up for the 16 CARs to 560 data points. The noise level was set to 0.25. The conditions were our standard conditions. The values for Z_i and Ex as well as K_i are provided by Fig. 4, A and C, respectively. The fdx values (imprecisions) were fd1 = 7.022 (0.0354), fd2 = 7.42 × 10⁻³ (0.0289), fd3 = 1.11 × 10⁻⁴ (0.0357), and fd4 = 7.30 × 10⁻³ (0.0262). The brackets in the legends indicate closely similar data points and curves. The big gray double arrow illustrates that the CAR combination is varied.