Figure S3.
Oleoyl-CoA activation of TALK-2 K2P channels.(A and B) Representative current traces (left) and analyzed currents at +80 mV plotted over time (right) of TALK-2 channels measured in voltage ramps between −80 and +80 mV in excised inside-out patches of Xenopus oocytes using K+ or Rb+ (red) bath solutions and in the presence of 0.1 µM (A), 1 µM, 3 µM, 5 µM, 10 µM, and 30 µM (B) oleoyl-CoA or 5 mg ml−1 BSA for washout.

Oleoyl-CoA activation of TALK-2 K2P channels. (A and B) Representative current traces (left) and analyzed currents at +80 mV plotted over time (right) of TALK-2 channels measured in voltage ramps between −80 and +80 mV in excised inside-out patches of Xenopus oocytes using K+ or Rb+ (red) bath solutions and in the presence of 0.1 µM (A), 1 µM, 3 µM, 5 µM, 10 µM, and 30 µM (B) oleoyl-CoA or 5 mg ml−1 BSA for washout.

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