Noradrenaline causes T-wave inversion . Repolarization maps of a heart that was perfused with Ringer’s solution in situ (no humoral agents) and in which the head and neck had been removed (no activity from the central nervous system). While the gradient of repolarization became steeper at higher temperatures, the administration of noradrenaline changed the repolarization vector and caused T-wave inversion (n = 1).