Figure 12.

Concentration dependence for Zn2+ effects on tail-current kinetics. (A) Concentration dependence for the increase in deactivation time-constants at −50 mV (τdeact(−50 mV)), determined under the experimental conditions indicated on the right (same cells as in Fig. 9). (B) Mean tail-current traces recorded under the experimental conditions indicated above in the absence (black) and presence (orange) of 100 µM (top) or 300 µM (bottom) free Zn2+. They have been scaled to their maximum amplitude to highlight kinetic changes.

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