Determination of TRPV1 structures by single-particle cryo-EM. (A) The 3.4 Å map of TRPV1 determined by single-particle cryo-EM is shown in a side view (left) and a cytoplasmic view (right). (B) The “resolution revolution” in cryo-EM has led to a recent explosion of structures deposited at EMDB. The plot is available at https://www.ebi.ac.uk/pdbe/emdb/statistics_main.html/.