Figure S2. BTP-2 sensitivity of... | Rockefeller University Press

Figure S2.

BTP-2 sensitivity of store-operated and constitutive Mn2+ quench in FDB fibers.(A–D) Representative superimposed traces of fura-2 fluorescence (A and B) and quantitative analyses of the maximum rate of Mn2+ quench (C and D) during application of 0.5 mM Mn2+ followed by 0.5 mM Mn2+ supplemented with either 10 µM BTP-2 (blue) or DMSO (red) vehicle in FDB fibers from CASQ1-null mice in the presence (+depletion; A and C) or absence (−depletion; B and D) of prior store depletion. Data are shown as mean ± SEM; *, P < 0.05. Numbers in bars (n) indicate the number of FDB fibers analyzed. Number of mice: n = 2 CASQ1-null.

BTP-2 sensitivity of store-operated and constitutive Mn²⁺ quench in FDB fibers. (A–D) Representative superimposed traces of fura-2 fluorescence (A and B) and quantitative analyses of the maximum rate of Mn²⁺ quench (C and D) during application of 0.5 mM Mn²⁺ followed by 0.5 mM Mn²⁺ supplemented with either 10 µM BTP-2 (blue) or DMSO (red) vehicle in FDB fibers from CASQ1-null mice in the presence (+depletion; A and C) or absence (−depletion; B and D) of prior store depletion. Data are shown as mean ± SEM; *, P < 0.05. Numbers in bars (n) indicate the number of FDB fibers analyzed. Number of mice: n = 2 CASQ1-null.

This Feature Is Available To Subscribers Only