Figure 9.
hV3 shows dual morphologies in the aggregated state. Representative SEM images of aggregated hV3 WT. (A and B) Here, hV3 shows the presence of amyloidogenic fiber-like aggregates presented in different magnifications (low magnification, A; high magnification, B). (C and D) hV3 also shows the formation of globular mesh-type aggregates (low magnification, C; high magnification, D). Hence, the aggregated sample of hV3 contains a mixture of structured and amorphous aggregates. Note that we diluted the aggregated samples considerably for SEM experiments to observe well-separated images of the amyloid fibrils.