Figure 4.
Figure 4. Effects of PI(3,4,5)P3 on IF in SN cells isolated from rabbit heart. (A and B) Traces of IF activation in (A) control cells and (B) cells infused with 1 µM PI(3,4,5)P3 in the patch pipette. (C) Boltzmann fit of IC activation curves for IF. Control (n = 10), V1/2 = −83.6 mV, K = 19.2 ± 0.89 mV; PI(3,4,5)P3 (n = 25), V1/2 = −73.7 mV, K = 19.3 ± 0.35 mV. Summarized data show mean ± SEM.

Effects of PI(3,4,5)P3 on IF in SN cells isolated from rabbit heart. (A and B) Traces of IF activation in (A) control cells and (B) cells infused with 1 µM PI(3,4,5)P3 in the patch pipette. (C) Boltzmann fit of IC activation curves for IF. Control (n = 10), V1/2 = −83.6 mV, K = 19.2 ± 0.89 mV; PI(3,4,5)P3 (n = 25), V1/2 = −73.7 mV, K = 19.3 ± 0.35 mV. Summarized data show mean ± SEM.

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