IALV contractile parameters of all Ano1^smKO and c-KitCreER^T2 Ano1KO. Summary of IALV contractile parameters frequency (A), amplitude (B), and tone (C) from SMMHC-CreER^T2-Ano1KO, SMArTTa-tetOCre-Ano1KO, and the constitutive smMHC^Cre/eGFP-Ano1KO. Contractile parameters for SMArTTa-tetOCre-Ano1KO from two IALVs collected 4 mo after induction as opposed to 2 wk. *, #, and $ denote P values < 0.05 when compared with Ano1fl/fl controls (n = 22) for SMMHC-CreER^T2-Ano1KO (n = 27), smMHC^Cre/eGFP-Ano1KO (n = 7), and SMArTTa-tetOCre-Ano1KO (n = 6), respectively. Summary of IALV contractile parameters frequency (D), amplitude (E), and tone (F) from c-KitCreER^T2-Ano1KO mice (n = 5) and Ano1fl/fl control mice (n = 22).