Figure 3.
Figure 3. Updated 1982 mechanism of 5-HT transport accounting for antiport with H+. In path A, 5-HT is transported across the membrane together with Na+ and Cl-. Return of the transporter to the outward facing state would occur by outward transport of H+ by path B, or K+ by path C. *T represents a hypothetical conductive transporter state in equilibrium with TiK+.

Updated 1982 mechanism of 5-HT transport accounting for antiport with H+. In path A, 5-HT is transported across the membrane together with Na+ and Cl-. Return of the transporter to the outward facing state would occur by outward transport of H+ by path B, or K+ by path C. *T represents a hypothetical conductive transporter state in equilibrium with TiK+.

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