Rods contribute to WT cone photocurrents. Superimposed photocurrents from individual cones with stimuli ranging from 40 to 6,000 P*/flash. (A) WT cone with strong rod coupling. Red trace represents the dark-adapted response to a flash bleaching 1,520 P*. Inset: Red trace from A compared with blue trace, giving photoresponse to same flash but in the presence of a background light bleaching 9,300 Rh* s⁻¹ (or 3,400 M-opsin pigment molecules bleached s⁻¹ in the smaller cones). (B) Recovery of photocurrent in Gnat1^−/− cone is monophasic, lacking the slower secondary component seen in A. (C) Similar result for Cx36^−/− cone. Note that time base is faster in B and C than in A.