Figure 5. The CTDs of Cav2.1 and Cav2.2 distinguish their abilities to undergo CDF. (A–E) As in Fig. 2 (double-pulse protocol) and Fig. 3 (100-Hz protocol) except cells transfected with Cav2.2 channels with the CTD of Cav2.1 (A–C) or Cav2.1 channels with the CTD of Cav2.2 (D and E). In C, interpulse voltage was −140 mV. Gray line representing strong CDF of Cav2.1 ICa (from Fig. 3 A) is overlaid for comparison. Data represent mean ± SEM.
Figure 5.

The CTDs of Cav2.1 and Cav2.2 distinguish their abilities to undergo CDF. (A–E) As in Fig. 2 (double-pulse protocol) and Fig. 3 (100-Hz protocol) except cells transfected with Cav2.2 channels with the CTD of Cav2.1 (A–C) or Cav2.1 channels with the CTD of Cav2.2 (D and E). In C, interpulse voltage was −140 mV. Gray line representing strong CDF of Cav2.1 ICa (from Fig. 3 A) is overlaid for comparison. Data represent mean ± SEM.

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