Strength of the CD-I correlates with inactivation parameters. (A and B) I_pk PIP₂ potentiation versus I_ss/I_pk (A) and I_ss/I_pk (B) for inactivating mutants versus τ_inact, for Kir6.2 CD-I mutations (data from Fig. 4). (C) Correlation between Kir2.1 PIP₂ potentiation and DiC8-PIP₂ EC₅₀. The corresponding correlation coefficient (r) and coefficient of determination (r²) from each linear regression fit (red) are provided (inset). Data are presented as means ± SEM.