Figure 2.

The gain-of-function effect of the I9′A mutation on GLIC. (A–D) Macroscopic-current responses of WT GLIC (A and B) and the I9′A mutant (C and D) to 5-s or 1-min pulses of pH 4.5 extracellular solution. The displayed traces are representative recordings obtained in the outside-out or whole-cell configuration at −80 mV.

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