Three-state model (Duke) predictions of T1 − T2 transitions and corresponding bound cross-bridge distributions. (A) Force transients after rapid length shortening per half sarcomere, yo = 7.35 nm, predicted by MUSICO (black lines), Duke (green line), and Duke PL (red line) models. The force transients during the first 20 ms after quick decrease in length of per half sarcomere are shown (inset). (B) The bound cross-bridge distributions and state probability density distribution functions at times at 1 and 5 ms after T1 change of length. The arrows signify net binding fluxes that cause different rates of force redevelopment. The evolution of cross-bridge distributions at early times ( < 1 ms) and at later times ( > 5 ms) are shown in Fig. S7.