The number of I7-GFP glomeruli increased in TMEM16B KO mice. (A) The top row shows a series of three consecutive sagittal sections, where a single I7-GFP glomerulus (pointed by the arrows) is present in a WT mouse. The bottom row shows a series of consecutive sections from a KO mouse, where several glomeruli were observed (arrows). (B) Bar plot representing the total number of glomeruli per animal that significantly increased in the KO (8 ± 1, seven mice) compared with WT (4.8 ± 0.5, seven mice); unpaired t test: *, P = 0.015. (C) Bar plot representing the number of heterogeneous glomeruli in WT (black bar, 3.4 ± 3, seven mice) and in KO mice (blue bar, 5 ± 1.4, seven mice). Data are shown as mean ± SEM.