Figure 4.
Evoked activity recorded with the suction pipette technique in OSNs from WT and KO mice. (A and B) Single-cell suction electrode recordings from a dissociated WT (A) and KO (B) OSN stimulated with a 1-s pulse of 1 mM IBMX. Insets show responses on an expanded time scale. The recording bandwidth was 0–5,000 Hz to display APs. (C–F) Differences in the response were quantified for the number of spikes (C), the duration of the train of elicited spikes (D), the delay of the first spike (E), and maximal firing frequency (F). Mean ± SEM; number of experiments is indicated in parentheses. Unpaired t test: *, 0.01 < P < 0.05.