Transduction current recorded with the suction pipette technique from isolated OSNs. (A and B) Single-cell suction electrode recordings from a dissociated WT (A) and KO (B) OSN stimulated with a 1-s pulse of 1 mM IBMX in Ringer’s solution and in the presence or absence of 300 µM NFA, a Cl⁻ channel blocker. (C and D) Suction peak currents measured in control, in the presence of NFA and after washout (C) and ratio of the response in the presence and absence of NFA (D). Mean ± SEM, n = 6 for WT and KO. Unpaired t test: **, P < 0.01.