Figure 6.
![Figure 6. Comparison of Na+ and Cl− permeation properties through the pores of the WT∙WT channel (abbreviated as WT) and the K584Q mutant. (A) I-V curves of the wild-type channel (left) and the K584Q mutant (right) in three [NaCl]i conditions: 140 mM (black traces), 84 mM (red traces), and 42 mM (blue traces). The reversal potentials (Erev) in each recording are better shown in the inset of each panel. (B) Averaged values of Erev of WT∙WT (black), K584Q mutant (red), E698C-WT(K584Q) (green), and E698C(K584Q)-WT (blue) in 140, 84, and 42 mM [NaCl]i. Values of Erev of various channels in the same ionic conditions (Table S1) were not significantly different from one another (P > 0.05, one-way ANOVA).](https://cdn.rupress.org/rup/content_public/journal/jgp/148/5/10.1085_jgp.201611651/5/jgp_201611651_fig6.jpeg?Expires=1767745318&Signature=QZQGE6m6IxmNWvd~2kasNIaxmffWRhNXRChJ5RD2Czom95pPsJftyC7-PVLwng6csf1hrd65k22S~TK5dmI-B6pZOGcN5QOE9wqbC1y-f-gk-u2mtf8yAgPP35L9ipxMZK7uze80~5Y~sa0-i3i0G28HkCduTnNWng42Pycniq-F1VlXmz2mxdQuvGLuTak~HSeZAwfUBR~t8y96WwusWkoJbh2WCHHciYha09Dr7pE5uhXMMdR-ucULITSHMdnL2dml0HHvhjpXEX~BiR-Ot2WMczKvg6lpAJb2HiBsR-gc4~-cTx6fxoFQ7jEqyyXy6-3hL2gpFQk67IE0mMJe6g__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Comparison of Na+ and Cl− permeation properties through the pores of the WT∙WT channel (abbreviated as WT) and the K584Q mutant. (A) I-V curves of the wild-type channel (left) and the K584Q mutant (right) in three [NaCl]i conditions: 140 mM (black traces), 84 mM (red traces), and 42 mM (blue traces). The reversal potentials (Erev) in each recording are better shown in the inset of each panel. (B) Averaged values of Erev of WT∙WT (black), K584Q mutant (red), E698C-WT(K584Q) (green), and E698C(K584Q)-WT (blue) in 140, 84, and 42 mM [NaCl]i. Values of Erev of various channels in the same ionic conditions (Table S1) were not significantly different from one another (P > 0.05, one-way ANOVA).
