Figure 2.
![Figure 2. Recording traces of wild-type TMEM16A and tandemly linked dimers. Channel currents were induced by a test [Ca2+] pulse (the middle pulse, indicated by red horizontal lines) and two saturating [Ca2+] pulses (indicated by blue horizontal lines) before and after the test pulse for inducing maximal current. Red traces: 40 mV; black traces: −40 mV. (A) Wild-type TMEM16A (namely, WT∙WT). (B) E698C∙E698C. (C) E698C-E698C. (D) E698C-WT.](https://cdn.rupress.org/rup/content_public/journal/jgp/148/5/10.1085_jgp.201611651/5/jgp_201611651_fig2.jpeg?Expires=1767753969&Signature=xGGow7aHjWE8A6~S2TUVXipDi49cQlmlYLsXFQFnOx4N9TMPj1ln4nenhGf3XOfGQZHZ4toZ8lehRUFUQzbdIGtmjnfJgkUg7aietYdsc4OuFJQz9OtLaXD61gXzY--2nLk5Dhf07L-LD5XcA3O1LXIXJcHE8NtE8jGJ-esSqmH0B49Xs~VdmE4XXnctgl9XP6VbGEwZQwwp~9kOW25K7goGjB2J1hvknyXN-Zxa3uGPAJAEVRBIGAghQL1voIVtaHhXsGidWHyYtN2MOTavPlzUQKZUU7bVErG5MMRqEtDjmg9Agir2H-K-1~VYZqbFikcOH5CIc7MP5LnE78eS0w__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Recording traces of wild-type TMEM16A and tandemly linked dimers. Channel currents were induced by a test [Ca2+] pulse (the middle pulse, indicated by red horizontal lines) and two saturating [Ca2+] pulses (indicated by blue horizontal lines) before and after the test pulse for inducing maximal current. Red traces: 40 mV; black traces: −40 mV. (A) Wild-type TMEM16A (namely, WT∙WT). (B) E698C∙E698C. (C) E698C-E698C. (D) E698C-WT.
