Comparison of Cd²⁺-induced inhibition between 98C and 98C/341C. (A and B) In inside-out patches, the inhibitory effect of Cd²⁺ on 98C (A) and 341C (B) currents dissipated in seconds upon removal of Cd²⁺ from the perfusate. (C) Summary of the inhibitory effect of Cd²⁺ on 98C, 341C, and 98C/341C. Note a lack of statistically significant difference in the percent inhibition between the double mutant and either single mutant (P > 0.3). Mean ± SEM is shown.