Cross-linking 102C and 341C with Cd²⁺. (A) 5 µM Cd²⁺ nearly abolished all 102C/341C currents in an inside-out patch, which recovered at an indiscernible rate upon washout of Cd²⁺ in the presence of EGTA. DTT, however, readily restored the currents. (B) Comparison of Cd²⁺-induced inhibition for 102C, 341C, and 102C/341C. Mean ± SEM is shown. ***, P < 0.001.