Figure 8.
Figure 8. AutoR-mediated responses are amplified by activation of Nav channels. (A) Representative traces of average laser-evoked ASPs in control (black) and in TTX (gray; 400 nM). Summary plot of TTX effect on (B) ASP amplitude (control: 3.1 ± 1 mV; TTX: 1.9 ± 1 mV; paired t test, **, P < 0.01; n = 7 sites), (C) τRise (control: 13 ± 4 ms; TTX: 9 ± 4 ms; paired t test, **, P < 0.01; n = 7 sites), and (D) τDecay (control: 145 ± 88 ms; TTX: 75 ± 48 ms; paired t test, *, P < 0.05; n = 7 sites). Black dots represent mean ± SEM.

AutoR-mediated responses are amplified by activation of Nav channels. (A) Representative traces of average laser-evoked ASPs in control (black) and in TTX (gray; 400 nM). Summary plot of TTX effect on (B) ASP amplitude (control: 3.1 ± 1 mV; TTX: 1.9 ± 1 mV; paired t test, **, P < 0.01; n = 7 sites), (C) τRise (control: 13 ± 4 ms; TTX: 9 ± 4 ms; paired t test, **, P < 0.01; n = 7 sites), and (D) τDecay (control: 145 ± 88 ms; TTX: 75 ± 48 ms; paired t test, *, P < 0.05; n = 7 sites). Black dots represent mean ± SEM.

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