The cyclic transmural pressure induced the vasodilation in the precontracted coronary and skeletal muscular small arterial segments. P_int was cyclically varied from ∼90 to 0 mmHg and later maintained constant at ∼90 mmHg. P_ext was maintained constant at 0 mmHg and later cyclically varied from 0 to ∼90 mmHg. P_int–P_ext was similar regardless of intraluminal or extraluminal variations. (A) The vasodilation in coronary and skeletal muscle arteries. ODCA was the OD of coronary arterial segment, which was tracked in real time during variations of transmural pressure. VC, vasoconstrictor (endothelin-1); ΔD_vc, diameter change by vasoconstrictor; ΔD_ctp, peak diameter change by cyclic transluminal pressure; ΔD_edv, peak diameter change by endothelium-dependent vasodilator; BK and ACh, bradykinin and acetylcholine (endothelium-dependent vasodilator). ODSMA was the OD of skeletal muscular arterial segment, which was tracked in real time during variations of transmural pressure. Vasodilation (%) = ΔD_ctp/ΔD_vc. The defined abbreviations here are applied in all subsequent figures. (B) The vasodilation in response to the magnitude of the cyclic transmural pressure.