Figure 3.
Low Ca2+ exposure decelerates the flash responses in WT rods but mimics the effects of light adaptation in the GCAP−/− rods. Representative rod response families to 2-ms flashes of light recorded from an isolated WT retina in normal (A) and low Ca2+ (B) solution. Flash strength ranges (R* per rod) are indicated in each panel. Responses to identical flash are shown in dark blue. Rod flash response families in normal (C) and low Ca2+ (D) solution recorded from a GCAP−/− mouse retina. Responses to identical flash are shown in light blue. Rods were allowed to reach a steady state after solution changes before the response families were recorded.
