Organization of cardiac sarcomeres, showing the localization of SR ryanodine receptor calcium release channels at the ends of the sarcomere, development of a calcium gradient, and the location of MyBP-C bound to thick filaments toward the sarcomere center. From Previs et al. Sci. Adv. 2015;1:e1400205 (20 February 2015). This work is licensed under CC BY-NC (http://creativecommons.org/licenses/by-nc/4.0/).

Organization of cardiac sarcomeres, showing the localization of SR ryanodine receptor calcium release channels at the ends of the sarcomere, development of a calcium gradient, and the location of MyBP-C bound to thick filaments toward the sarcomere center. From Previs et al. Sci. Adv. 2015;1:e1400205 (20 February 2015). This work is licensed under CC BY-NC (http://creativecommons.org/licenses/by-nc/4.0/).

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