Spontaneously occurring single APs in β2 KO CCs exhibit slowed repolarization and persistent afterdepolarizations. (A) Traces are averaged spontaneous APs for BK_i and β2 KO (red) CCs. APs from individual cells were aligned on the time of peak AP potential. β2 KO cells exhibit reduced peak AP amplitude and a pronounced depolarizing afterpotential. (B) Traces compare spontaneous APs in BK_i and BK_s, revealing a reduced AHP in the BK_s cells. (C) APs from BK_i and Slo1 KO CCs are shown, revealing a larger peak amplitude and prolonged repolarization phase in the Slo1 KO cells.