Figure 11. Properties of evoked single APs. (A) Mean (red circles) and individual values of peak AP amplitude are shown for BKi, BKs, and β2 KO cells. Errors are SD. Differences were evaluated with a t test statistic. A–C use 150-pA current injection. (B) The membrane voltage at the time of the peak AHP in the BKi cells was determined for BKi, BKs, and β2 KO cells. The dotted line at −50 mV indicates the holding potential. (C) AP durations (duration at half peak AP) are plotted for BKi, BKs, and β2 KO cells. (D) Peak AP amplitudes are compared for BKi, Slo1 KO, and β2 KO cells. D–F use 250-pA current injection. (E) AHP amplitudes are compared for BKi, Slo1 KO, and β2 KO cells. (F) AP durations are compared for BKi, Slo1 KO, and β2 KO cells. (G) Peak AP amplitudes are compared for BKi and β2 KO at both the 150- and 250-pA injections. (H) AHP amplitudes are compared for the 150- and 250-pA injections for BKi and β2 KO cells.
Figure 11.

Properties of evoked single APs. (A) Mean (red circles) and individual values of peak AP amplitude are shown for BKi, BKs, and β2 KO cells. Errors are SD. Differences were evaluated with a t test statistic. A–C use 150-pA current injection. (B) The membrane voltage at the time of the peak AHP in the BKi cells was determined for BKi, BKs, and β2 KO cells. The dotted line at −50 mV indicates the holding potential. (C) AP durations (duration at half peak AP) are plotted for BKi, BKs, and β2 KO cells. (D) Peak AP amplitudes are compared for BKi, Slo1 KO, and β2 KO cells. D–F use 250-pA current injection. (E) AHP amplitudes are compared for BKi, Slo1 KO, and β2 KO cells. (F) AP durations are compared for BKi, Slo1 KO, and β2 KO cells. (G) Peak AP amplitudes are compared for BKi and β2 KO at both the 150- and 250-pA injections. (H) AHP amplitudes are compared for the 150- and 250-pA injections for BKi and β2 KO cells.

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