Figure 2. Voltage dependence for peak INa, normalized by maximal on-gating charge displacement, Qon_max. Symbols show mean and SEM for WT (black; n = 15), R669H (blue; n = 34), and R672G (red; n = 18). Oocytes for which the maximal INa occurred at a voltage of less than −30 mV were excluded to reduce the effect of inadequate voltage-clamp control. Error bars represent ± SEM.
Figure 2.

Voltage dependence for peak INa, normalized by maximal on-gating charge displacement, Qon_max. Symbols show mean and SEM for WT (black; n = 15), R669H (blue; n = 34), and R672G (red; n = 18). Oocytes for which the maximal INa occurred at a voltage of less than −30 mV were excluded to reduce the effect of inadequate voltage-clamp control. Error bars represent ± SEM.

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