Figure 7. DIV voltage-sensor movement as... | Rockefeller University Press

Figure 7.

$Figure 7. DIV voltage-sensor movement as a mechanism for fast inactivation from closed states. Representative current traces for wild-type and DIV-CN channels in response to a depolarization to −20 mV as shown in Fig. 1 B overlaid with their respective time courses for development of fast inactivation at −20 mV as shown in Fig. 3 B. Currents were scaled to the fraction of fast inactivated channels at the time of peak current. Development of fast inactivation precedes current rise for DIV-CN but not wild-type channels.$

DIV voltage-sensor movement as a mechanism for fast inactivation from closed states. Representative current traces for wild-type and DIV-CN channels in response to a depolarization to −20 mV as shown in Fig. 1 B overlaid with their respective time courses for development of fast inactivation at −20 mV as shown in Fig. 3 B. Currents were scaled to the fraction of fast inactivated channels at the time of peak current. Development of fast inactivation precedes current rise for DIV-CN but not wild-type channels.