Figure 10.

Differences in Δ[Ca2+] and Δ[Ca2Trop] waveforms in frog simulations that included both components of the release function (continuous traces) and only the first component of the release function (broken traces). In A, the troponin reaction did not include Mg2+ competition (simulated with the release function from Fig. 7); in B, the reaction in Fig. 3 was used (simulated with the release function from Fig. 8). Among any three traces of similar type (broken or continuous), the traces with the largest, intermediate, and smallest peak values are the averages, respectively, of the changes in the three radial compartments adjacent to the z-line, the three radial compartments in the middle of the thin filament, and the three radial compartments at the m-line end of the thin filament (compare with Fig. 2). The length of the half-sarcomere in the simulation was 2.0 µm (as in Figs. 6–9).

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