Figure 8.
Figure 8. Relationship between PCl and PNa of HEK293 cells expressing WT and engineered TMEM16F constructs. The permeabilities were obtained as described in the legend of Fig. 7. For expressing permeability in the conventional units of cm/s, the values given in Table 2 have been recalculated using the empirical approximation that 106 pF corresponds to a membrane area of 1 cm2. The linear fit to all data is given by PNa = 0.334 × PCl (±SD = 0.028), R2 = 0.903, and n = 15.

Relationship between PCl and PNa of HEK293 cells expressing WT and engineered TMEM16F constructs. The permeabilities were obtained as described in the legend of Fig. 7. For expressing permeability in the conventional units of cm/s, the values given in Table 2 have been recalculated using the empirical approximation that 106 pF corresponds to a membrane area of 1 cm2. The linear fit to all data is given by PNa = 0.334 × PCl (±SD = 0.028), R2 = 0.903, and n = 15.

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