Figure 5.
![Figure 5. Anion selectivity of the mTMEM16F-induced current. (A and B) Representative anion selectivity current traces recorded in whole-cell configuration after stimulation with 250 µM [Ca2+]i of mock (A)- and mTMEM16F-transfected (B) HEK293 cells. (C and D) Mean relative anion permeabilities (PX/PCl) for mock (C)- and mTMEM16F-transfected (D) HEK293 cells. PX/PCl are presented as a mean of seven to nine cells and are tested by one way ANOVA; “*” indicates significant (P < 0.05) difference from PCl, and “†” indicates significant difference (P < 0.05) between the relevant anion permeabilities when tested with paired t test. Only experiments in which the anion permeabilities were paired were included in the statistical test.](https://cdn.rupress.org/rup/content_public/journal/jgp/141/5/10.1085_jgp.201210861/4/jgp_201210861_fig5.jpeg?Expires=1768873254&Signature=0GuOZ94n99y5sp0AY6io8dGwebtCXLODX9nZgFpq5l6HF9lNSuUXbYPEae5Ftz9Vx17fN~i6bsRyKZ1Wd8g2xpgI1lzmI7ZldTAVAkoK02ph2beVpnbP-s0Z0Ery5lIkMERlA7qUu~EbiR1jK3mV83beziAdbyDfEDOFR572zgFptYuvi5tM7KAlOhHONqDNjeooGkiHbM6eX6VNTI9~aXubLbefKLbYiXZUWR~E1x5p~9WgFkiTRJsTUa2a-kuBRleC6RAQx2CxgDO8le-cnAAdH5Ww4lAXsDOuAEssTuwecDXouK9qBlZ4LdBs00HHUafzRSvEwyiPcXkC-0gVBg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Anion selectivity of the mTMEM16F-induced current. (A and B) Representative anion selectivity current traces recorded in whole-cell configuration after stimulation with 250 µM [Ca2+]i of mock (A)- and mTMEM16F-transfected (B) HEK293 cells. (C and D) Mean relative anion permeabilities (PX/PCl) for mock (C)- and mTMEM16F-transfected (D) HEK293 cells. PX/PCl are presented as a mean of seven to nine cells and are tested by one way ANOVA; “*” indicates significant (P < 0.05) difference from PCl, and “†” indicates significant difference (P < 0.05) between the relevant anion permeabilities when tested with paired t test. Only experiments in which the anion permeabilities were paired were included in the statistical test.
