![Figure 5. Water permeability effects in the diffusion-limited model. (A) Time course of [K+]e and de for the indicated Pf and Da. Parameters: PK = 1.2 × 10−5 cm/s, JKno = 10−8 mol/cm2/s, Δtn = 0.1 s, da = 10 µm, and de = 2 µm. (B) Effect of magnitude of neuroexcitation. Computations as in B, but with JKno = 5 × 10−8 mol/cm2/s to increase [K+]e from 5 to 30 mM. (C) Effect of duration of neuroexcitation. Computations as in C, with PK = 1.3 × 10−5 cm/s, JKno = 8 × 10−10 mol/cm2/s, and Δtn = 10 s. (D) Spatial distributions of [K+]a and osmolarity (Φa) in astrocyte cytoplasm for the indicated Pf and Da, with parameters as in C.](https://cdn.rupress.org/rup/content_public/journal/jgp/141/1/10.1085_jgp.201210883/4/jgp_201210883_fig5.jpeg?Expires=1767655239&Signature=K8s9h7uKgrld4r91-lUJl-xbHKPZ0kmqUMVxMcPsSJkDbsSU-2dDPgisS11xH7qfEGe-RB0fIZUKMtN~SCS1noqYDlKAefmtiWW3kuNd3CsHun3hajgVt067QBtGOJ0MhZ~vSapCZGMut6YjqfNB~5FWy-qIrZ7kbUwh06Aug5YFz~W29fkKCXhWUoLx05ydbFDKCiVh9IQURRKyWhNtg6XlKVXWh7rRDyb0P~1bQ2XKUeASvVFzEWbn6xSnTgaaCj1f3gmC7aZoQDoQlcrF~xNWYFJ5raDgRvvKh80W73FlvQ~3rVeTdJ5-J3IWPmD9ca0E3rAyzPG6LuCHzSK0xA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Figure 5.
Water permeability effects in the diffusion-limited model. (A) Time course of [K+]e and de for the indicated Pf and Da. Parameters: PK = 1.2 × 10−5 cm/s, JKno = 10−8 mol/cm2/s, Δtn = 0.1 s, da = 10 µm, and de = 2 µm. (B) Effect of magnitude of neuroexcitation. Computations as in B, but with JKno = 5 × 10−8 mol/cm2/s to increase [K+]e from 5 to 30 mM. (C) Effect of duration of neuroexcitation. Computations as in C, with PK = 1.3 × 10−5 cm/s, JKno = 8 × 10−10 mol/cm2/s, and Δtn = 10 s. (D) Spatial distributions of [K+]a and osmolarity (Φa) in astrocyte cytoplasm for the indicated Pf and Da, with parameters as in C.
