Figure 1.

Morphological and functional analyses of neonatal and 10-d-old WT and cMyBP-C−/− hearts. (A–D) H&E-stained thin sections of 1-d-old WT (A), 10-d-old WT (B), 1-d-old cMyBP-C−/− (C), and 10-d-old (D) mouse hearts. Bar, 1 mm. (E–G) Heart/body weight ratios (E), ejection fraction (F), and cardiac output (G) of 1- and 10-d-old WT and cMyBP-C−/− mice are shown. Error bars indicate SEM. *, P < 0.05 versus age-matched WT (Student’s t test; day 1 WT, n = 6; day 1 cMyBP-C−/−, n = 7; day 10 WT, n = 6; day 10 cMyBP-C−/−, n = 7).

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