Figure 3.

Pathways for Ca2+ transport in mammalian mitochondria. RC, respiratory chain; MCU, mitochondrial Ca2+ uniporter; MICU1, mitochondrial Ca2+ uptake 1; NCLX, Na+–Ca2+ exchanger; HCE, H+–Ca2+ exchanger; PTP, permeability transition pore. For explanation, see text.

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