K_V4.2 channels are insensitive to depletion of PI(4,5)P₂ by Dr-VSP. (A) Current traces of a cell expressing K_V4.2 and Dr-VSP. Black indicates before activation of Dr-VSP, and red indicates 4 s after activation of Dr-VSP. (B–D) Same protocol as in A but with coexpression of KChIP1 (B), KChIP1 and DPP6-s (C), or KChIP2 (D).