Figure 4.
Figure 4. Y464A hEAG1 channels exhibit enhanced inactivation. (A) Voltage-pulse protocol and corresponding Y464A hEAG1 currents. (B) Test-pulse currents (during time indicated by a solid bar in A) are shown on an expanded time scale. Test currents elicited after Vpre of −130, −85, −70, and −40 mV are labeled. A fast inactivating component of current is evident when Vpre ≥ −70 mV.

Y464A hEAG1 channels exhibit enhanced inactivation. (A) Voltage-pulse protocol and corresponding Y464A hEAG1 currents. (B) Test-pulse currents (during time indicated by a solid bar in A) are shown on an expanded time scale. Test currents elicited after Vpre of −130, −85, −70, and −40 mV are labeled. A fast inactivating component of current is evident when Vpre ≥ −70 mV.

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