Figure 9.

Concentration dependence of the kinetics of spermidine block in the D172N mutant. (A) Single-channel currents recorded in the presence of 0.03, 0.1, and 0.3 µM [spermidine]i at +50 mV in the D172N mutant. (B) Histograms for the substate and blocked times. (C) Dose dependence of association and dissociation rates.

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