Figure 2.

Conduction through Kir1.1 channels in inside-out patches with symmetrical Rb+ concentrations. (A) Inward currents with −100 mV across the patch at different [Rb+]. (B) i-V relationships for different [Rb+]. Lines through the data points have no theoretical meaning. (C) Single-channel currents at −100 mV as a function of ion concentration. The line represents the best fit of Eq. 1 to the data, with imax = 1.8 ± 0.1 pA and Km = 26 ± 4 mM. (D) imax and Km, measured as in C, as a function of voltage.

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