Figure 8.
Block of Ba2+ permeation by K+. Ba2+ block datasets were recorded as in Fig. 5, at different concentrations of external K+. (A) Nonconducting time histograms are shown (log-binned except for 10 µM K+ data, which is binned linearly to show its rising phase). (B) Behavior of fast/slow time constants (top) and amplitudes (bottom) of block-time distributions. Curves have no theoretical meaning, except for the 1/τs curve, which plots Eq. 7. Gray shading on the amplitude plot indicates the range of K+ concentrations where the fast amplitude, in reversing sign, becomes too small to observe and thereby produces a single-exponential block-time distribution.