Open and closed dwell-time histograms at 20°C are well described by two open and five closed exponential components, respectively. (A–D) Open-time (A and C) and closed-time (B and D) histograms at 40 (top) and 100 mV (bottom; 25 bins per decade). The distributions are well described (continuous lines) by the sums of two open exponential components and five closed exponential components (dashed lines). Open-time constants (and normalized areas) are 0.31 ms (0.53) and 0.67 ms (0.47) at 40 mV and 0.87 ms (0.42) and 2 ms (0.58) at 100 mV. Closed-time constants (and normalized areas) are 0.21 ms (0.39), 1.4 ms (0.28), 5.8 ms (0.27), 23 ms (0.066), and 2,256 ms (0.00064) at 40 mV and 0.18 ms (0.39), 0.80 ms (0.32), 2.3 ms (0.26), 11 ms (0.021), and 6,314 ms (0.00019) at 100 mV.