Figure 3.
![Figure 3. The relationship between [CFTRinh-172] and the closing rate. Mean open times at different concentrations of CFTRinh-172 were obtained from single-channel kinetic analysis, as described in Materials and methods. Each data point represents values determined from 7–10 patches. This relationship follows a saturation function, suggesting the existence of an additional step after the binding of the inhibitor to the open channel.](https://cdn.rupress.org/rup/content_public/journal/jgp/136/6/10.1085_jgp.201010518/5/jgp_201010518_lw_fig3.jpeg?Expires=1770241396&Signature=W~CJtiFzhqlQcz8JaqKz68QT0c5v5cwuB7v-t8ik-Dugcr9-3QitzytdBMRmu5SQMfQKUWI68itT62i6J0AkxzQetf5Y2nOWB0XKarOOwUBcD60VI8Pr4EKYcc-JmJxDKqhdyHU8PQ9hi5erWdaVLwum2jlZOGxexitqj5psLKaYK7tC9~ispJjmMkLHo~hqFhWI3B7-1Y~icUWEuKyCwVE2Oe5Lcpu2lM9br2OnP2t1CkBXljyk-b7m12eowNu9xm3WYrVOluCvO58DVr60tXVuWeZU2WaIfSsXXFRZZllYRZuQKibhlhBl3dVJhkzDrs005I-JKxeC0-FIGy7FrA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
The relationship between [CFTRinh-172] and the closing rate. Mean open times at different concentrations of CFTRinh-172 were obtained from single-channel kinetic analysis, as described in Materials and methods. Each data point represents values determined from 7–10 patches. This relationship follows a saturation function, suggesting the existence of an additional step after the binding of the inhibitor to the open channel.
