Figure 8.

Transients and flux elicited by a pulse train. The figure illustrates the kinetic analysis of Ca2+ flux for transients elicited by a train of depolarizing pulses (illustrated in A) to + 40 mV, at 30 Hz, lasting 2.5 s. (A and B) Fluorescence transients in WT and dCasq-null cells. (C and D) Corresponding evolution of [Ca2+]cyto and Rnet. (E) Evolution of amount released, R(t). The peaks of the increases in all magnitudes repeat the differences between WT and null illustrated in previous figures. Specifically, fluorescence and [Ca2+]cyto(t) can be compared with the corresponding records in Fig. 2, Rnet and R(t) with those in Fig. 7. ID: WT, 012809b_10; null, 020509b_8.

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